There are a variety of different waterproof, spill-proof keyboards. Some look like regular keyboards, so you wouldn't even know that they're waterproof. You can type on them without any problems because they look and feel like standard QWERTY keyboards.
Other waterproof keyboards are flexible and they are somewhat difficult to use. Those that are flexible feel more like buttons on a calculator instead of a keyboard.
You can also find keyboards that have a backlight so that you can use them in low-light situations. These are perfect for radiology suites and call rooms.